Biology

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1
1665; Published the book, "Micrographia" in which he gave about 60 observations about the cells in detail using a compound microscope.
Robert Hooke
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1665; He coined the term ‘cell’.
Robert Hooke
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1674; Discovery of the existence of single-cell organisms. Upon examining pond water, he observed dozens of protists, which he called 'animalcules' as well as spirogyra (green algae).
Anton Van Leeuwenhoek
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1838; 1) All organisms are made up of cells. 2) Cells are the basic units of life. He made these conclusions after comparing observations of plant and animal cells.
Matthias Schleiden
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1839; Proposed The Classical Cell Theory. It implied that this relationship was a specific and lawful one, i.e. that germs of a certain kind, all else being equal, would produce adult organisms of the same kind, and vice versa.
Theodor Schwann
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The Cell Theory
  • All known living things are made up of cells.
  • A cell is the structural and functional unit of all living things.
  • All cells come from pre-existing cells by division. Spontaneous generation does not occur.
  • Cells contain hereditary information (DNA) which is passed on to new cells during cell division
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1855; Proposed that new cells are formed only from cells that already exist. "Omnis cellula e cellula*". Proposed the more recent version of the Cell Theory.
Rudolf Virchow
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The smallest structural unit of an organism that is capable of independent functioning.
Cell
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It is composed of a nucleus, cytoplasm and various organelles surrounded by a selectively permeable membrane.
Cell
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Major Structural Features of Eukaryotic Cells
  • Plasma Membrane
  • Nucleus
  • Membrane-bound Organelles
  • Cytosol
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It provides different local environments that facilitate the occurence of complex metabolic reactions or even incompatible processes, simultaneously and in the correct sequence within the same cell.
Compartmentalization
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Also known as the 'cell membrane' defines the boundary of the cell and retain its contents.
Plasma Membrane
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Houses the DNA that directs cellular activities.
Nucleus
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Where various cellular functions are localized.
Organelles
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The semi-fluid substance in which all the organelles are suspended. Fits between the nucleus and cell membrane and consists mainly of water excluding the organelles in it.
Cytosol
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Cytoplasmic Organelles
  • Endoplasmic reticulum
  • Golgi apparatus
  • Mitochondria
  • Lysosomes
  • Cell membrane
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Make up protists (unicellular organisms which include protozoa), fungi, plants and animals. Has no plasmids.
Eukaryotic Cells
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They have a true Nucleus that houses their DNA and contain numerous membrane-bound organelles where multiple biochemical processes can occur simultaneously and independetly.
Eukaryotic Cells
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A small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA.
Plasmids
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An example of which would be bacteria and archaebacteria.
Prokaryotic Cells
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Have a single compartment enclosed by a cell membrane. They lack true nuclei and all the cell components such as DNA, RNA, ribosomes and other molecules are not separated from each other in the cell's interior.
Prokaryotic Cells
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Endoplasmic Reticulum
  • Smooth ER
  • Rough ER
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Cytoplasmic Inclusions
  • Ribosomes
  • Centrioles and Centrosomes
  • Cytoskeleton
  • Microtubules
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Tabular and non-granular structure due to the absence of ribosomes. It manufactures and metabolizes lipids. It also facilitates in the break down of drugs and alcohols.
Smooth ER
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Has the presence of ribosomes. It is the site of protein synthesis. It is in charge of the folding, quality control and dispatch of proteins.
Rough ER
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Processing, packaging and sorting of secretory material for use within and outside the cell.
Golgi apparatus
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It is the powerhouse the cell. It contains enzymes—chemical oxidation of food molecules and produces energy in ATP (Adenosine Triphosphate).
Mitochondria
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Small spherical membrane-bound organelles which contain a number of enzymes
for intracellular digestion.
Lysosomes
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Thin barrier that forms a boundary between separating an individual cell from the external environment.
Plasma membrane
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A small structure within a cell, consisting of fluid enclosed by a lipid bilayer. They form naturally during the processes of secretion*, uptake** and transport of materials within the cytoplasm.
Vesicles
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An energy-consuming process that expels secretory vesicles containing nanoparticles (or other chemicals) out of the cell membranes into the extracellular space.
Exocytosis
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A cellular process for ingesting and eliminating particles larger than 0.5 μm in diameter, including microorganisms, foreign substances, and apoptotic cells. It is found in many types of cells and it is, in consequence an essential process for tissue homeostasis.
Phagocytosis
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Are specialized for carrying out oxidative reactions using molecular oxygen. They generate hydrogen peroxide, which they use for oxidative purposes—destroying the excess by means of the catalase they contain.
Peroxisome
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Are protein factories of the cell. They can be found in the Rough ER and they synthesize protein molecules.
Ribosomes
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Small dense region of cytoplasm that serves as the main microtubule organizing center.
Centrioles and Centrosomes
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A network of protein fibers that support the shape of the cell and anchors organelles to fixed locations.
Cytoskeleton
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Are long slender protein tubes. They form the cytoskeleton of the cell.
Microtubules
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The storehouse of DNA inside the cell. Protects the DNA at all times.
Nucleus
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Nucleus includes
  • Nuclear envelope
  • Nucleolus
  • Nuclear pores
  • Chromatin
  • DNA
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Can be found in PLANT CELLS only:
  • Cell wall
  • Large central vacuole
  • Chloroplasts
  • Plastids
  • Lysosomes
  • Centrioles
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A two-layered outer limit of the nucleus separating it from the cytoplasm.
Nuclear Envelope
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Responsible for ribosome formation.
Nucleolus
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Selective channels between the cytoplasm and the inside of the nucleus. Allows molecules which contain the correct localization signal to pass in and out.
Nuclear pores
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Made up of DNA and proteins and form chromosomes during cell division.
Chromatin
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Contains the genes inherited by the offspring from their parents.
Chromosomes
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Its main component is cellulose. It provides structural support and gives the plant its rigid shape.
Cell wall
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Cell wall has:
  • Primary wall
  • Secondary wall
  • Tertiary wall
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Forms during the growth period of the cell.
Primary cell wall
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Forms when the growth of the cell ceases.
Secondary cell wall
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Large and more centrally located in the plant cell. Store enzymes and waste products.
Vacuole
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are double-membrane organelles that are responsible for manufacturing and storing of food. These often contain pigments that are used in photosynthesis.
Plastids
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Tissues
  • Epithelial tissue
  • Connective tissue
  • Muscle tissue
  • Nervous tissue
  • Hot tissue
  • Paper tissue
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Are co-axial membranous channels that cross walls of adjacent plant cells, linking the cytoplasm, plasma membranes and ER of cells and allowing direct cytoplasmic cell-to-cell communication of both small molecules and macromolecules.
Plasmodesmata
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Covers all body surfaces, lines body cavities and hollow organs and the major
tissue in glands. Closely packed, flat cells with very little intercellular space and only a small amount of intercellular substance. Does not contain blood vessels.
Epithelial tissue
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Intercellular junctions that attach EPITHELIAL TISSUES:
  • Adhering junction
  • Tight junction
  • Gap Junction
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When there is anchoring of the cytoskeleton of one cell to another.
Adhering junction
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type of junction that prevents leaking.
Tight junction
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Communication between cells.
Gap Junction
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Helps in the breakdown of alcohol.
Cytochrome P450
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Types of Epithelial Tissues
  • Simple epithelium
  • Stratified epithelium
  • Pseudostratified epithelium
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Type of epithelial tissue that is only one cell thick
Simple epithelium
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Type of epithelial tissue that is two or more cells thick
Stratified epithelium
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Type of epithelial tissue that is composed of a single layer of cells that are of different sizes.
Pseudostratified epithelium
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Shapes of Epithelial Tissues
  • Squamos
  • Cuboidal
  • Pseudostratified
  • Columnar
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Shape of epithelial tissue that lines the lungs, capillary walls and blood
vessels. It forms membrane that allows selective diffusion of materials to pass through. It is flat.
Squamos
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Shape of epithelial tissue that lines the kidney tubules and absorbs molecules. It is a cube shape.
Cuboidal
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Shape of epithelial tissue that lines the trachea and aids in movement of mucus. It is shaped like alternating strata.
Pseudostratified
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Shape of epithelial tissue that lines the small intestine. Its primary functions: secretion, excretion, and absorption. It is shaped like columns.
Columnar
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How does epithelial tissue renew?
They can renew and move on top of the five layers of thick skin in about a month. If
with injury, various hormones—epidermal growth factor—will speed up the renewal process during wound healing (a week or two).
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Binds structure together. It also forms a framework and support for organs and the body as a whole. Additionally, it helps repair damaged tissues.
Connective Tissue
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Types of Connective tissue
  • Cartilage
  • Bone
  • Blood
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It provides flexibility, shock absorption, and reduction of friction on load bearing surfaces. These can be mostly seen in joints.
Cartilage
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