11665; Published the book, "Micrographia" in which he gave about 60 observations about the cells in detail using a compound microscope.
Robert Hooke
21665; He coined the term ‘cell’.
Robert Hooke
31674; Discovery of the existence of single-cell organisms. Upon examining pond water, he observed dozens of protists, which he called 'animalcules' as well as spirogyra (green algae).
Anton Van Leeuwenhoek
41838; 1) All organisms are made up of cells. 2) Cells are the basic units of life. He made these conclusions after comparing observations of plant and animal cells.
Matthias Schleiden
51839; Proposed The Classical Cell Theory. It implied that this relationship was a specific and lawful one, i.e. that germs of a certain kind, all else being equal, would produce adult organisms of the same kind, and vice versa.
Theodor Schwann
6The Cell Theory
- All known living things are made up of cells.
- A cell is the structural and functional unit of all living things.
- All cells come from pre-existing cells by division. Spontaneous generation does not occur.
- Cells contain hereditary information (DNA) which is passed on to new cells during cell division
71855; Proposed that new cells are formed only from cells that already exist. "Omnis cellula e cellula*". Proposed the more recent version of the Cell Theory.
Rudolf Virchow
8The smallest structural unit of an organism that is capable of independent functioning.
Cell
9It is composed of a nucleus, cytoplasm and various organelles surrounded by a selectively permeable membrane.
Cell
10Major Structural Features of Eukaryotic Cells
- Plasma Membrane
- Nucleus
- Membrane-bound Organelles
- Cytosol
11 It provides different local environments that facilitate the occurence of complex metabolic reactions or even incompatible processes, simultaneously and in the correct sequence within the same cell.
Compartmentalization
12Also known as the 'cell membrane' defines the boundary of the cell and retain its contents.
Plasma Membrane
13Houses the DNA that directs cellular activities.
Nucleus
14Where various cellular functions are localized.
Organelles
15The semi-fluid substance in which all the organelles are suspended. Fits between the nucleus and cell membrane and consists mainly of water excluding the organelles in it.
Cytosol
16Cytoplasmic Organelles
- Endoplasmic reticulum
- Golgi apparatus
- Mitochondria
- Lysosomes
- Cell membrane
17Make up protists (unicellular organisms which include protozoa), fungi, plants and animals. Has no plasmids.
Eukaryotic Cells
18They have a true Nucleus that houses their DNA and contain numerous membrane-bound organelles where multiple biochemical processes can occur simultaneously and independetly.
Eukaryotic Cells
19A small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA.
Plasmids
20An example of which would be bacteria and archaebacteria.
Prokaryotic Cells
21Have a single compartment enclosed by a cell membrane. They lack true nuclei and all the cell components such as DNA, RNA, ribosomes and other molecules are not separated from each other in the cell's interior.
Prokaryotic Cells
23Cytoplasmic Inclusions
- Ribosomes
- Centrioles and Centrosomes
- Cytoskeleton
- Microtubules
24Tabular and non-granular structure due to the absence of ribosomes. It manufactures and metabolizes lipids. It also facilitates in the break down of drugs and alcohols.
Smooth ER
25Has the presence of ribosomes. It is the site of protein synthesis. It is in charge of the folding, quality control and dispatch of proteins.
Rough ER
26Processing, packaging and sorting of secretory material for use within and outside the cell.
Golgi apparatus
27It is the powerhouse the cell. It contains enzymes—chemical oxidation of food molecules and produces energy in ATP (Adenosine Triphosphate).
Mitochondria
28Small spherical membrane-bound organelles which contain a number of enzymes
for intracellular digestion.
Lysosomes
29Thin barrier that forms a boundary between separating an individual cell from the external environment.
Plasma membrane
30A small structure within a cell, consisting of fluid enclosed by a lipid bilayer. They form naturally during the processes of secretion*, uptake** and transport of materials within the cytoplasm.
Vesicles
31 An energy-consuming process that expels secretory vesicles containing nanoparticles (or other chemicals) out of the cell membranes into the extracellular space.
Exocytosis
32A cellular process for ingesting and eliminating particles larger than 0.5 μm in diameter, including microorganisms, foreign substances, and apoptotic cells. It is found in many types of cells and it is, in consequence an essential process for tissue homeostasis.
Phagocytosis
33Are specialized for carrying out oxidative reactions using molecular oxygen. They generate hydrogen peroxide, which they use for oxidative purposes—destroying the excess by means of the catalase they contain.
Peroxisome
34Are protein factories of the cell. They can be found in the Rough ER and they synthesize protein molecules.
Ribosomes
35Small dense region of cytoplasm that serves as the main microtubule organizing center.
Centrioles and Centrosomes
36A network of protein fibers that support the shape of the cell and anchors organelles to fixed locations.
Cytoskeleton
37Are long slender protein tubes. They form the cytoskeleton of the cell.
Microtubules
38The storehouse of DNA inside the cell. Protects the DNA at all times.
Nucleus
39Nucleus includes
- Nuclear envelope
- Nucleolus
- Nuclear pores
- Chromatin
- DNA
40Can be found in PLANT CELLS only:
- Cell wall
- Large central vacuole
- Chloroplasts
- Plastids
- Lysosomes
- Centrioles
41A two-layered outer limit of the nucleus separating it from the cytoplasm.
Nuclear Envelope
42Responsible for ribosome formation.
Nucleolus
43Selective channels between the cytoplasm and the inside of the nucleus. Allows molecules which contain the correct localization signal to pass in and out.
Nuclear pores
44Made up of DNA and proteins and form chromosomes during cell division.
Chromatin
45Contains the genes inherited by the offspring from their parents.
Chromosomes
46Its main component is cellulose. It provides structural support and gives the plant its rigid shape.
Cell wall
47Cell wall has:
- Primary wall
- Secondary wall
- Tertiary wall
48Forms during the growth period of the cell.
Primary cell wall
49Forms when the growth of the cell ceases.
Secondary cell wall
50Large and more centrally located in the plant cell. Store enzymes and waste products.
Vacuole
51are double-membrane organelles that are responsible for manufacturing and storing of food. These often contain pigments that are used in photosynthesis.
Plastids
52Tissues
- Epithelial tissue
- Connective tissue
- Muscle tissue
- Nervous tissue
- Hot tissue
- Paper tissue
53Are co-axial membranous channels that cross walls of adjacent plant cells, linking the cytoplasm, plasma membranes and ER of cells and allowing direct cytoplasmic cell-to-cell communication of both small molecules and macromolecules.
Plasmodesmata
54Covers all body surfaces, lines body cavities and hollow organs and the major
tissue in glands. Closely packed, flat cells with very little intercellular space and only a small amount of intercellular substance. Does not contain blood vessels.
Epithelial tissue
55Intercellular junctions that attach EPITHELIAL TISSUES:
- Adhering junction
- Tight junction
- Gap Junction
56When there is anchoring of the cytoskeleton of one cell to another.
Adhering junction
57type of junction that prevents leaking.
Tight junction
58Communication between cells.
Gap Junction
59Helps in the breakdown of alcohol.
Cytochrome P450
60Types of Epithelial Tissues
- Simple epithelium
- Stratified epithelium
- Pseudostratified epithelium
61Type of epithelial tissue that is only one cell thick
Simple epithelium
62Type of epithelial tissue that is two or more cells thick
Stratified epithelium
63Type of epithelial tissue that is composed of a single layer of cells that are of different sizes.
Pseudostratified epithelium
64Shapes of Epithelial Tissues
- Squamos
- Cuboidal
- Pseudostratified
- Columnar
65Shape of epithelial tissue that lines the lungs, capillary walls and blood
vessels. It forms membrane that allows selective diffusion of materials to pass through. It is flat.
Squamos
66Shape of epithelial tissue that lines the kidney tubules and absorbs molecules. It is a cube shape.
Cuboidal
67Shape of epithelial tissue that lines the trachea and aids in movement of mucus. It is shaped like alternating strata.
Pseudostratified
68Shape of epithelial tissue that lines the small intestine. Its primary functions: secretion, excretion, and absorption. It is shaped like columns.
Columnar
69How does epithelial tissue renew?
They can renew and move on top of the five layers of thick skin in about a month. If
with injury, various hormones—epidermal growth factor—will speed up the renewal process during wound healing (a week or two).
70Binds structure together. It also forms a framework and support for organs and the body as a whole. Additionally, it helps repair damaged tissues.
Connective Tissue
71Types of Connective tissue
72It provides flexibility, shock absorption, and reduction of friction on load bearing surfaces. These can be mostly seen in joints.
Cartilage