Anatomy Unit 8: Endocrine System

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Endocrine
The system of glands in your body that releases hormones into the bloodstream (into the body)
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Exocrine
Out of the body
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Hormone
Hormones are chemicals released from a gland in small amounts and are carried through the bloodstream. They only affect cells with receptors
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Target cell
The cells that hormones are trying to change
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Hormonal stimulation
Glands are encouraged by hormones secreted by other hormones
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Humoral Stimulation
Levels of nutrients and ions in the blood cause glands to secrete hormones
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Neural Stimulation
Nerve impulses cause glands to secrete hormones
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Negative Feedback
A loop that decreases output to move back to homeostasis
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Positive Feedback
A loop that causes the body to move away from homeostasis
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Hypersecretion
Too much hormone is released
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Hyposecretion
Not enough hormone is released
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(Adrenal) Cortex
Outer layer of adrenal gland, produces Glucocortocoids, which raise ion levels and regulate stress response
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(Adrenal) medulla
Inner layer of adrenal gland, produces epinephrine and norepinephrine, which regulate fight or flight response
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Water soluable hormone
Amino acids that can't pass through the cell membrane so binds to receptors on outside of cell
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Lipid soluable hormone
Steroids which can pass directly through the cell membrane whose receptors are on the inside of the cell
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Islets of Langerhans
Groups of cells on endocrine part of pancreas which produce insulin and glucagon
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Anterior Pituitary
Front lobe on underside of brain, makes thyroid stimulating hormone, adrenocorticotropic hormone, growth hormone, melanocyte stimulating hormone, prolactin, and gonadotropins
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Posterior pituitary
Posterior bulb on underside of brain, produces antidiueretic ormone vasopressin) and oxytocin
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Pineal Gland
Coned-shaped gland near the cerebellum that produces melatonin
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Thyroid
Gland near base of neck in a butterfly shape. Produced calcitonin (reduces ca levels). Produces thyroid hormones (thyroxine and triidothyronine) which regulate metabolism
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Parathyroid
Attatched to back of thyroid gland and produced parathyroid hormone, which raises calcium levels
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Adrenal
Glands atop each kidney. Has an outer and inner later. Produces epinephrine and norepinephrine (fight or flight) and glicorortocoids (ion levels)
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Pancreas
Has endocrine and exocrine ducts. Endocrine part made of islets of Langerhans which make insulin and glucagon to lower or raise blood sugar
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Thymus
A gland near the sternum that matures immune cells (especially T-cells)
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Testes
Male reproductive organs that make testostorone. Produces sex cells and sex hormones
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Ovaries
Female reproductive organs that makes estrogen and progesterone. Produces sex xells and sex hormones
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Thyroid Stimulating (TSH)
Secreted by anterior pituitary, makes thyroid make thyroxine
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Adrenocorticotropic (ACTH)
Secreted by anterior pituitary, stimulates adrenal glands (cortisol)
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Growth Hormone (GH)
Secreted by anterior pituitary, stimulates growth in bones and muscles
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Melanocyte Stimulating (MSH)
From anterior pituitary, stimulated melanocytes to make melanin
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Prolactin (PRL)
From anterior pituitary, stimulates production of breast milk
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Antidiuretic (ADH)
From posterior pituitary, increases water retention in kidneys, decreasing urine production
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Luteinizing (LH)
From anterior putuitary, a gonadotropin that stimulates the release of sex hormones
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Follicle simulating (FSH)
From anterior pituitarym a gonadotropin that stimulates egg or sperm production
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Oxytocin (OT)
From posterior pituitary Contracts the uterus in childbirth and promotes the release of breast milk
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Melatonin
From pineal gland, promotes sleep
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Calcatonin
From thyroid gland, reduces calcium levels in blood
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Thyroxine (T3)
A thyroid hormone from the thyroid, regulates metabolism
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Parathyroid hormone
From parathyroid gland, raises calcium levels
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Epinepherine
From adrenal gland and medilla, regulates fight or flight
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Norepinephrine
From adrenal gland (medulla) regulates fight or flight
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Glucocorticoids
From adrenal gland (cortex) controls ion levels
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Insulin
From pancreas beta cells, lower blood sugar levels
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Glucagon
From pancreas alpha cells, raise blood sugar levels
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Thymosin
From thymus gland, is involved in development of the immune system
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Estrogen
(Women) From gonads, maturation of reproductive organs and secondary sex characteristics
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Progesterone
(Women) From gonads, responsible for breast development and menstral cycle
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Testosterone
(Men) From gonads, reproductive, secondary sex organs, production of sperm
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How do negative and positive feedback loops differ? What is an example of each in the endocrine system?
Negative feedback loops try to maintain the body's homeostasis, while positive work to push it further from homeostasis. Example of negative: Ca levels in blood drop, PTH stimulates calcium release from bones, Ca levels rise, and calcitonin stimulates Ca absorption in bones. Example of pos: baby puts project on cervix > contraction begins > oxytocin is released > baby is born
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How do the endocrine and exocrine glands differ? Which gland from this unit contains both types?
Exocrine glands secrete substances into ducts, endocrine secrete substances into bloodstream. Pancreas has endocrine and exocrine glands
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Why do hormones not affect all cells they encounter throughtout the body?
Because they only affect the cells which have receptors for them
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Explain how the hypersecretion and hyporsecretion of a specific hormone would affect the body.
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