Anatomy Unit 2: Cellular Structure & Function

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1
Prokaryote
Single-celled organisms/single cells, no nucleus nor membrane
2
Eukaryote
Have larger and more complex cells than prokaryotes, with DNA, membranes, and largest are .1mm to 1mm
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Phospholipid
Make up membrane–hydrophilic phosphate head, pydrophobid fatty acid tail
4
Why are cells limited in their ability to grow in size?
Because their volume grows faster than their surface area, which means that they cannot consume or excrete enough to keep up, so they divide instead
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How does the semi-permeable structure of the plasma membrane dictate its function?
Only some materials can pass through it. The bilayer means that hydrophillic molecules have to go through specific protein channels if they want to get in, whereas hydrophobic don't.
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Cholesterol
Hydrophobic molecule that in embeded in the inner layer of the membrane/lipid bilyaer, increases mebrane stability.
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Glycocalyx
Sugar covering, "cellular fingerprint". Identifies cells as being native to your body, made out of carbohydrates.
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What are the functions of proteins? (9)
Defense, storage, motor, sensory, regulatory, enzymes, structural, signaling, transport.
(Dying Squirrels Might See Rather Enigmatic Santas Subsequent To (death))
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Tight junction
A junction around a cell made of proteins to prevent fluids and molecules from moving between cells (bladder, intestines).
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Desmosomes
Strong cell adhesion made of proteins that reduces possibility of tearing and provides stability, in areas with high movement and tension
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Gap junction
Allows for small molecules to pass through for communications w/ rest of body (heart)
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Enzymes
Increase rate of chemical reactions
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Difference between passive and active transport
Passive transport does not require energy (ATP); active does because it is moving against the concentration gradient
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Diffusion
Movement from areas with areas with high concentrations of solutes to low concentration
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Osmosis
Diffusion of water
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Isotonic
A solution with the same concentration as cytoplasm, has no net effect
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Hypotonic
A solution with a lower concentration than cytoplasm
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Hypertonic
A solution with higher concentration than cytoplasm
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Facilitated diffusion
Type of passive diffusion that happens w/transmembrane proteins, used for specific proteins like glucose
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Vesicular transport
Membranous sacs used to move large amounts of material
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Endocytosis
Imports of vesicular transport
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Exocytosis
Exports to vesicular transport
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Cytosol
Fluid that contains all nutrients, ions, and proteins in cell, fluid that all organelles are in
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Phagocytosis
"Cell eating" engulfing of cells or food (ex. white blood cells and bacteria)
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Cytoskeleton
Protein filaments that provide structure to cell
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Villi
A cytoskeleton structure in some cells, finger-like projections made to increase surface area. For cells with a lot of material to imprt, like intestines
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Centriole
Cylindrical structure of cytoskeletal structures. Moves chromosomes.
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Cilia
Long, slender extensions of plasma membrane
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Flagella
Longer than cilia, found in humans only in sperm cells
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Ribosomes
Produce all proteins, either floating freely or attatched to Rough endoplasmic reticulum
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Smooth ER
Endoplasmic reticulum with no ribosomes, produces lipids and carbohydrates. Network of membranes connected to nucleus' membrane.
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Rough ER
Endoplasmic reticulum that has ribsosomes permenantly attatched to it, which it then packages to the Golgi. Network of membranes connected to nucleus' membrane.
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Golgi Apparatus
Made of several flattened discs, and makes vesicles. (Post office of the cell)
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3 Types of Vesicles
Secretory, lysosomes, peroxisomes
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Secretory
Type of vesicle that packagesormones or enzymes to be released (or...secreted...) outside the cell
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Lysosomes
Type of vesicle that has digestive enzymes to break down ingested materials or old organelles
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Peroxisomes
Type of vesicle that breaks down fatty acids (aka lipids), which releases hydrogen peroxide. Hydrogen peroxide is a free radical (it has an unpaired electron) so it damages other cells, but peroxisomes also contain catalase to break down hydrogen peroxide.
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Mitochondria
Makes ATP by extracting it from glucose via aerobic respiration
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Nuclear Envelope
Double-layer membrane around nucleus
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Nucleolis
Part in nucleus that makes ribosomes
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2 ways DNA is stored
Chromatin (loose coils) and chromosomes (tightly coiled)
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Integral protein
Proteins that go all the way through lipid bilayer (although some only come through one side) to transport things in and out of cells
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Perepheral protein
Attatched to inside or outside of lipid bilayer
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Phospholipid bilayer
Composes most of plasma membrane--2 layers of phospholipids with hydrophobic tails in the middle and hydrophilic heads, so only hydrophobic molecules can get through easily
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Organelle
Basically a little organ, or the organs inside the cell.
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What makes cancer cells different from regular ones?
Cancer cells don't respond regularly to the body's control mechanisms (they have an irregular shape, form tumors, and ESPECIALLY they keep dividing when they don't need to.
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Mitosis
How non-reproductive cells divide
48
Explain the process of protein synthesis and the organelles involved.
1. Nucleus (has the instructions for proteins, send out via rDNA) 2. Rough ER (protein is made by the ribosomes, sent out in vesicle) 3. Golgi (packed, tagged, and shipped out still in vesicle) 4. Exocytosis (kinda membrane) (protein is sent into the larger organism.
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