1What is GIomerulonephritis?
inflammation of the glomeruli
2Acute Primary Causes? Chronic
Infection
♡ Bacteria: streptococcus, sepsis, klebsiella pneumoniae
♡ Viruses: dengue fever, varicella, parvovirus, hep B & C, HIV
3Acute Secondary Causes?. o o
Systemic
♡ lupus, chronic liver conditions (Hep B & C), autoimmune hepatitis, cirrhosis
♡ nephropathy, vasculitis, HIV associated G.
4Chronic Causes?
Sometimes Unknown
Infection
Inflammation
Impaired renal perfusion
5Signs & Symptoms
Lethargy / Irritation
Pallor
Headaches
N/V
AB / Flank pain
Anorexia
Edema - periorbital, generalized, pulmonary
6Urinary Manifestations
- decreased urine output
- Dysuria
- Hematurin
7Diagnosis
- Urinalysis : hematuria, proteinuria
- Microsopic examination of the urine : Dysmorphic erythrocytes, RBC cell cast, epithelial cast
- 24 hoururine collection : qauntify protein excretion rate → increased to 500mg - 3g / 24hrs
8Both A & C
Increased creatinine & BUN
9To identify the cause?
- Immunological pannel
- CT-Scan of abdomen : structure abnormalities
10Report to HCP
signs of fluid over load
11Symptoms of uremia
severe fatigue, N/V, ALOC