ch 8

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1
Metabolism
is the totality of an organism’s chemical reactions
2
Chemical reactions occur
anytime two or more atoms, ions, or molecules collide in such a way that they produce a new substance
3
metabolic pathway begins with a... and ends with a...
specific molecule, product
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Energy is...
the capacity to cause change
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free energy
The portion of a system’s energy that can perform work
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chemical reactions that release energy (downhill change)
exergonic reactions
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chemical reactions that takes in energy (not spontantious, up hill change is harder than downhill change)
endergonic reaction
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kinetic energy
energy an object possesses by being in motion
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entropy
a measure of disorder
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chemical energy
energy substances release when they undergo a chemical reaction
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energy that isnt kinetic is
potential energy
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potential energy, For example, a raised weight, and an arrow about to be shot
energy conserved within an object.
13
Energy coupling
the use of an exergonic process to drive an endergonic one
-ATP is key to this process
-in an exergonic reaction atp becomes adp as a phosphate is removed
-a reactant molecule aquires the phosphate from atp and the reaction can continue
14
ATP (adenosine triphosphate) is composed of
ribose (a sugar), adenine (a nitrogenous base), and three phosphate groups
15
A cell does three main kinds of work:
Chemical work

Transport work

Mechanical work
16
catalyst
a chemical agent that speeds up a reaction without being consumed by the reaction
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Enzyme
a catalytic protein
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catalysis
enzymes or other catalysts speed up specific reactions by lowering the EA barrier
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feedback inhibition
the end product of a metabolic pathway shuts down the pathway
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Cooperativity is
a form of allosteric regulation that can amplify enzyme activity
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Allosteric regulation may
either inhibit or stimulate an enzyme’s activity
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Allosteric regulation occurs when
a regulatory molecule binds to a protein at one site and affects the protein’s function at another site
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Competitive inhibitors
bind to the active site of an enzyme, competing with the substrate
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Noncompetitive inhibitors
bind to another part of an enzyme, causing the enzyme to change shape and making the active site less effective
25
Energy of action
energy needed to start a reaction
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