1Essential aa acronym
TIM LIV HK FW
2Essential Amino Acids
body can’t produce naturally, need through our environment/diet
3Nonessential amino acids
body can produce naturally
4What is the condition of arginine being non essential?
fully functioning urea cycle
5What is the condition of tyrosine being nonessential?
obtaining phenylalanine
6How can aspartate be synthesized?
through oxaloacetate
7How is alanine synthesized?
through pyruvate
8How can glutamate be synthesized?
through ketoglutarate
9What is the shikimate pathway?
The pathway for the synthesis of aromatic amino acids in plants and microorganisms. This pathway is not present in humans.
10What does glyphosate do?
blocks part of the shikimate pathway and ends in death of the plant/micro-organism
11Post-Translational Modifications (PTM)
side chains can be chemically modified
12What do you need for hydroxylation of proline?
vitamin C
13What happens when there is no vitamin c in the body?
scurvy
14Most amino acids exists as CATIONS at a very (acidic or basic) pH
acidic
15Amino acids as cations NH3 and COOH is
protonated
16Most amino acids exist as ANIONS as a very (acidic or basic) pH
basic
17Amino acids as anions NH3 and COOH is
deprotonated
18when pH is low, aa are
protonated
19when pH is high, aa are
deprotonated
20pH is less than PI
most molecules are cations
21pH is more than PI
most molecules are anions
22Learn How to Calculate pI
okay
23Peptide bond is..
rigid and planar
24what does rigid and planar mean?
1. shorter bond length
2. NO free rotation on peptide bond
3. 6 atoms on same plane
4. partial double bond feature because C-N is shorter than typical
25Which is favored? Cis or trans?
Trans
26Eq of pI
2 pI = pKcooh + pKnh3+