GATech BIOS 1208 Unit 3 - Chemical & Electrical Signals

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1
Ligands
The molecule that binds to a receptor
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Receptor
The site that a ligand binds to
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Juxtacrine Signaling (Direct Signaling)
Chemical signaling through direct contact (Gap junctions in animals, plasmodesmata in plants)
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Autocrine Signaling
Chemical signaling where a cell signals itself
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Paracrine Signaling
Chemical signaling where a cell signals a nearby cell
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Endocrine Signaling
Chemical signaling where a signal travels through the bloodstream
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Pheromones
Signals released into the environment to act on another individual
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Peptide Hormones
Small proteins that are hydrophilic hormones
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Amino Acid-Derived Hormones
Modified amino acids that are hydrophilic hormones
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Steroid Hormones
Small organic compounds with characteristic ring structures that are hydrophobic hormones
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Gas Hormones
Gases capable of acting as ligands that are hydrophobic hormones
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Signal Transduction
The intracellular process of a cell responding to signals through signaling pathways or signaling cascades
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Signal Amplification
The process where small amounts of hormones produce hundreds of strands of mRNA and proteins
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Positive Feedback Loop
The original signal is amplified as a result of the hormone being received
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Negative Feedback Loop
The original signal is inhibited as a result of the hormone being received
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Signaling Crosstalk
When two signals are received at the same time, the outcome can be different than if they were received separately
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Quorum Sensing
The process by which individual cells can monitor the density of their population, caused by an autoinducer hormone
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Glands
Locations where animal hormones are produced
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Pituitary Gland
"Master Gland" at the base of the brain
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Thyroid Gland
Gland located in the neck that produces hormones to regulate metabolism and growth
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Adrenal Glands
Two glands on the kidneys which produce different hormones
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Adrenal Cortex
Outer part of the adrenal glands responsible for producing mineralocorticoids and glucocorticoids
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Mineralocorticoids
Steroid hormones that increase reabsoprtion by kidneys to regulate water balance
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Glucocorticoids
Steroid hormones that deal with long-term stress response by increasing blood glucose levels through the liver
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Adrenal Medulla
Gland that produces epinephrine
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Epinephrine
Adrenaline, the fight or flight hormone that increases heart rate, breathing rate, blood pressure, and blood glucose levels
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Pancreas
Gland located between the stomach and small intestine that releases insulin and glucagon
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Insulin
Hormone that decreases blood glucose levels by promoting uptake in liver and muscle cells
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Glucagon
Hormone that increases blood glucose levels by promoting breakdown of glycogen
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Gonads
Gland found in the ovaries and testes that produces sex steroid hormones
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Diabetes Mellitus
Disease resulting from impaired insulin production
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Hyperglycemia
Technical term for high blood glucose levels
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Hypoglycemia
Technical term for low blood glucose levels
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Thyroxine
Growth and development hormone (T4)
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Triiodothyronine
Growth and development hormone, specifically initiates metamorphosis in vertebrates like amphibians (T3)
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Corpus Allatum
Gland in insects that produces juvenile hormone
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Prothoracicotropic Hormone
Hormone responsible for signaling the prothoracic gland in insects
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Prothoracic Gland
Gland in insects that releases ecdysone
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Ecdysone
Hormone in insects that promotes either molting or metamorphosis
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Glycogen
Stored glucose that helps with short-term stress
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Norepinephrine
Hormone that works with epinephrine to keep you alert and focused
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Adrenocorticotropic Hormone (ACTH)
Hormone that regulates the stress hormone cortisol
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Corticosteroids
Steroids that mediate long-term stress response
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Auxin
The youth hormone and growth regulator in plants
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Phototropism
Movement in response to light
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Gravitropism
Movement in response to gravity
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Apical Dominance
Inhibition of lateral bud formation
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Inhibition of Abscission
Inhibition of falling leaves
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Cytokinin
The cell division hormone in plants
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Gibberellin (GAs)
The growth hormone in plants responsible for stem, fruit, and seed growth and breaking dormancy in seeds
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Abscisic Acid (ABA)
The dormancy hormone in plants
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Ethylene
The aging hormone in plants that promotes fruit ripening, flower wilting, and leaf abscission
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Chromophore
Molecules that absorb specific wavelengths of light (Retinal is one of these)
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Phototropins (phot1 and phot2)
Blue light receptors in plants
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Acid Growth Hypothesis
The hypothesis behind phototropism, stating that auxin lowers pH which activates expansin, making the cell wall more flexible
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Blue Light
Type of light that causes plants to grow towards light
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Far-Red Light
Type of light that indicates shade to a plant
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Phytochrome (Pr and Pfr)
Chemoprotein responsible for red light and far-red light detection
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Amylase
An enzyme that breaks down starch
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Amyloplasts (Statoliths)
Specialized organelles that store starch granules
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Thigmotropism
Plant response to a touch stimulus, seen in vines or venus fly traps
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Neurons
Specialized cells that can transmit and receive electrical signals
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Glial Cells
Cells that support neurons
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Action Potential
Signals that transfer information in a neuron through a rapid change in membrane potential (electric charge)
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Neurotransmitters
Chemical signals released as a result of an action potential, they cause action potentials in other nearby neurons
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Soma
The cell body containing the nucleus and organelles of a neuron
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Dendrites
Tree-like structures that receive neurotransmitters from other neurons
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Axon
Tube-like structure where a neuron transmits an action potential
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Myelin
An insulator found on some axons that minimize dissipation and increases conductivity, increasing frequency of action potentials
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Synapses
Locations where singnals are transmitted
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Synaptic Cleft
Space between neuron synapses
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Axon Hillock
Site in a neuron where an action potential can potentially initiate
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Resting Potential
Membrane potential when a signal is not being transmitted
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Membrane Potential
Difference in charge between interior and exterior of a cell
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Sodium-Potassium Pump
A structure that transfers sodium out of the cell and potassium into the cell
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Potassium Leak Channel
A structure that allows for potassium to diffuse along its concentration gradient
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Depolarization
The change in membrane potential from negative to positive
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Hyperpolarization
The change in membrane potential from positive to negative
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Roughly -55 mV
Threshold potential
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Repolarization
The return of membrane potential from positive back to its natural state (not more negative) following the closure of sodium channels and opening of potassium channels
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Axon Diameter
Factor that affects frequency in invertebrates
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Nodes of Ranvier
The gaps between myelin that regenerate the action potential
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Saltatory Conduction
The term for the jumping of action potential between myelin and nodes of ranvier
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Voltage-Gated Calcium Channels
Channels responsible for releasing the molecules that initiate the signaling cascade resulting in the release of neurotransmitters
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Excitatory Postsynaptic Potentials (EPSPs)
Action potentials that depolarize the post-synaptic membrane, making another action potential more likely
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Inhibitory Postsynaptic Potentials (IPSPs)
Action potentials that hyperpolarize the post-synaptic membrane, making another action potential less likely
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Nerves
Bundles of nervous tissue
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Nerve Net
What jellyfish have instead of a brain
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Brain
Structure that processes information
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Spinal Cord
Structure that transmits information
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Interneurons
Neurons that receive information from afferent nerves and transmits information to efferent nerves
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Afferent Nerves (Sensory Nerves)
Collections of neurons that collect sensory information
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Efferent Nerves (Motor Nerves)
Collections of neurons that carry commands to the body
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White Matter
Myelinated tissue in the interior of the brain
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Grey Matter
Unmyelinated tissue in the exterior of the brain
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Cerebrospinal Fluid (CSF)
The fluid that the brain floats in
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Ventricles
Fluid filled cavities in the center of the brain lined with glial cells
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Cerebrum
The largest part of the brain responsible for concious thought
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Cerebral Cortex
The outer folds and ripples of the cerebrum
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Corpus Callosum
The thick fiber bundle that joins the hemispheres of the brain
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Diencephalon
Part of the brain that controls homeostasis and transmits sensory information
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Thalamus
The gateway to and from the cortex in the brain
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Hypothalamus
The master regulator of the body that controls the endocrine system
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Cerebellum
Part of the brain at the bottom that controlls balance and complex movements
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Brainstem
The part of the brain that connects the rest of the brain with the spinal cord, controlling several functions of the body that are unconcious
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Frontal Lobe
Lobe at the front of the brain that contains the olfactory bulb and motor cortex and also contributes to speech, attention, and decision-making
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Parietal Lobe
Lobe at the top of the brain that is involved in speech, reading, touch, and body orientation
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Occipital Lobe
Lobe located at the back of the brain primarily involved in vision
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Temporal Lobe
Lobe located at the bottom of the brain involved in processing sounds, containing the hippocampus
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Olfactory Bulb
The specific part of the brain the processes smells
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Motor Cortex
The specific part of the brain important for planning movement
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Neural Plasticity
The formation and loss of neural connections
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Prefrontal Cortex
Place in the brain where short-term memories are stored
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Hippocampus
Struture in the brain responsible for turning short-term memories into long-term memories
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Neurogenesis
The growth of new neurons
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Synaptogenesis
The growth of new synapses between neurons
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Synaptic Pruning
The destruction of synapses between neurons
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Dorsal Spinal Cord
The part of the spinal cord in which sensory information is transmitted
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Ventral Spinal Cord
The part of the spinal cord in which movement commands are transmitted
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Afferent Division
Part of the nervous system responsible for collecting sensory information
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Efferent Division
Part of the nervous system responsible for carrying out commands
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Somatic Nervous System
The nervous system that sends motor commands to voluntarily controlled cells
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Autonomic Nervous System
The nervous system that sends motor commands to involuntarily controlled cells
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Sympathetic Nervous System
The nervous system that controls short-term stress response
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Parasympathetic Nervous System
The nervous system that resets organ functions following a period of stress response
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Mechanoreceptors
Receptors that respond to physical deformation
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Photoreceptors
Receptors that respond to radiant energy (light)
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Chemoreceptors
Receptors that respond to specific molecules (taste and smell) also the oldest receptors
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Nociceptors
Receptors that respond to noxious stimuli, which is anything that would cause tissue damage
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Thermoreceptors
Receptors that respond to heat or cold
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Olfaction
Another name for the sense of smell
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Gustation
Another name for the sense of taste
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Vestibular (Equilibrium)
The name for the sense of balance and body position
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Somatosensation
Another name for the sensation of touch
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Pitch
What the frequency of sound waves are heard as
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Volume
What the amplitute of sound waves are heard as
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Outer Ear
The part of the ear that collects sound waves
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Auditory Canal
The structure in the ear that funnels sound waves to the ear drums
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Ear Drum
Structure in the ear that vibrates to transmit sound waves to the middle ear
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Ossicles
Three bones in the ear responsible for amplifying vibrations to transmit to the inner ear
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Cochlea
Structure in the ear that receives sound waves and contains mechanoreceptors
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Basilar Membrane
Flexible membrane found inside of the cochlea
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Hair Cells
The specific mechanoreceptors inside the cochlea and basilar membrane
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Stereocilia
Tiny protusions on the surface of hair cells responsible for creating action potentials when bent
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Vestibular System
System responsible for detecting position and the movement of the head
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Vestibular Labyrinth
Location of hair cells involved in the vestibular system
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Calcium Carbonate Crystals
Crystals embedded in gelatin that move in response to gravity
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Cupula
Gelatinous cup important for balance and head rotation
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Lateral Line
Structure in bony fish that can detect changes in pressure
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Statocyst
Structure that invertebrates use to detect balance
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Statoliths
Dense particles that activate hair cells as they move around
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Color
Wavelengths of light are perceived as different
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Brightness
Light wave amplitude is perceived as
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Eye Cups
Eyes found in flatworms that can detect direction of a light source
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Compound Eyes
Eyes found in arthropods that contain multiple lenses and cones and can detect shapes, patterns, and movements
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Pinhole Eyes
Eyes found in nautilus that have no lens and can see simple, low-resolution images
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Simple Eyes
Eyes found in cephalopods and vertebrates that contain a single lens and can produce high-resolution images
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Cornea
Transparent sheet of connective tissue in the eye, functions alongside the lens to focus light on the retina
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Iris
Pigmented ring of muscle that controls the amount of light entering the eye
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Pupil
Hole in the center of the iris
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Lens
Crystalline, curved structure that focuses light on the cornea
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Retina
Thin layer of photoreceptor cells and neurons in the eye
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Photoreceptor Cells
Light-detecting sensory cells
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Fovea
Site of retina with only cones, the highest area of visual resolution in the eye
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Optic Nerve
Axons of the ganglion cells make up the
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Retinal
Light-absorbing pigment molecule found in opsin
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Opsin
Protein that contains retinal
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Rhodopsin
The complex containing opsin and retinal that allows us to detect light and color
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S Opsin, M Opsin, L Opsin, and Rod Opsin
The four types of opsin
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Rod Opsin
The opsin found exclusively in rods that are useful for detecting movement
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Cytoskeleton
A network of filaments that supports the plasma membrane, gives a cell its shape, positions organelles, allows the cell to move, etc.
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Microfilaments (Actin Filaments)
Filaments that serve as the tracks for the motor protein myosin
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Microtubules
Tubulin proteins that serve as the tracks for the motor proteins kinesine and dynein
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Motor Proteins
Proteins that use ATP to "walk along" cytoskeletal filaments, essential for the movement of vesicles and transportation of proteins
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Myosin
Motor protein associated with actin microfilaments and helps move muscles
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Dynein
Motor protein associated with tubulin microfilaments and helps move cilia and flagella
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Kinesin
Motor protein associated with tubulin microtubulues and helps move vesicles and other cargos
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Flagella
Long, hair-like structures that are used to move an entire cell
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Cilia
Shorter structures found in large quantities that helps move materials along the cell surface
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Skeletal Muscle
Muscles that attach to bone and skin and control conscious movement
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Smooth Muscle
Muscle found in the walls of hollow organs and is involuntary muscle
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Cardiac Muscle Tissue
Muscle found only in the heart to maintain blood pressure
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Pacemaker Cells
Cells that are the reason the heart can beat without the nervous system's assistance
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Intercalated Discs
Structure within cardiac muscle that enables rapid action potentials to occur
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Muscle Fiber
Another name for each skeletal muscle cell
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Myofibrils
Structures within muscle fibers that contain sarcomeres
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Sarcomere
Structure within muscle fibers that contain a thick filament of myosin and a thin filament of actin that together cause contractions
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Z Discs
The structures that anchor actin filaments on both sides
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M Line
Structure that marks the center of the myosin filament
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Tropomyosin
Proteins that block the binding sites on both ends of the actin milament to prevent interactions when the muscles are at rest
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Troponin
Protein that is regulated by calcium, and regulates tropomyosin
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Sarcoplasmic Reticulum
Name for endoplasmic reticulum in muscle cells
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Acetylcholine (ACh)
Neurotransmitter released by a neuron to depolarize a muscle cell
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T-tubules
Tubulues that carry the action potential initiated by the depolarization of the muscle cell into the sarcoplasmic reticulum
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Calcium
Mineral responsible for the initiation of muscle contraction
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Tetanus
The maximum tension possible for a muscle
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Oxidative Muscle Fibers
Fibers that rely on oxidative phosphorylation to generate ATP, are often very slow to exhaust
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Glycolytic Muscle Fibers
Fibers that rely on glycolysis to generate ATP, are quick to fatigue
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Fast-Twitch Muscles
Muscles adapted for bursts of activity, composed of glycolytic muscle fibers
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Slow-Twitch Muscles
Muscles adapted for long-lived activities like supporting the body, composed of oxidative muscle fibers
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Antagonistic Pairs
Muscles must exist in these in order for a muscle to be pushed in on itself
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Flexor
Opposing muscle that pulls bones together
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Extensor
Opposing muscle that straightens two bones
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Hydrostatic Skeleton
Skeleton formed by the coelom found in soft-bodied animals, no constraints on contraction width
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Exoskeleton
External skeleton that consists of a hard encasement found in mollusks and arhtropods, muscles are jointed, and muscles have a limit on contraction width
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Endoskeleton
Internal skeleton that consists of hard, mineralized structures found in sponges, echinoderms, and chordates, muscles are jointed, and muscles do not have a constraint on contraction width
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Axial Skeleton
Part of the skeletal system in vertebrates consisting of the skull, vertebral column, and rib cage
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Appendicular Skeleton
Part of the skeletal system in vertebrates consisting of the shoulders, limb bones, pectoral girdle, and the pelvic girdle
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