Topic 1

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1
Functions of Blood
-brings oxygen and nutrients
-carries waste materials to be digested out the body
-carries horomones around the body
-fights infections
2
What does the Heart Do
Pump oxygenated and deoxygenated blood in and out
3
What is the Heart Made of
-cardiac tissue
-muscular walls that contract to pump blood
4
What is the Averages of the heart
70 beats per minute
Pumps 70mL of blood per beat
Standard BP is 120/80
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Heart Murmers
-When a valve is leaky and makes a swooshing sounds
-Can enlarge and overwhelm the heart over time
-Causes high heartrate and low volume of blood per beat
-Left AV Valve is the most common site
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Systole
Numerator of BP, is average 120
-Ventricles contract and blood is forced into arteries
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Diastole
Denominator of BP, is average 80
-Relaxation faze
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Blood Pressure
Regulated by the body contricting and dilating blood vessels.
Measure of pressure when ventricles contractelax

High BP leads to broken vessels and blood clots
Low BP leads to not enough blood reaching organs
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How does the Heartbeat work
SA Node (Upper right atrium) is a natural pacemaker
AV Node passes the nerve impluse and wraps around the ventricles
-Atria and ventricles contract in a smooth wave
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Pacemaker
-Used if the SA node fails to function properly and does not transmit impulses
-Consists of a battery and timer connected to an electrode
-Impulses speed up a slow heart and provide a steady beat
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Arteries
-Thick
-Carry blood AWAY from the heart
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Veins
-Thin
-Carry blood TOWARD the heart
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Capillaries
-Thin muscle walls conecting viens and arteries
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varicose Veins
Enlarged and twisted vein, leads to blood pooling

(reasoning behind why surgeons wear compression socks)
15
Things that Affect Heartrate
-Nervous system
-Excersize
-Temperature/Horomones
16
Pulmonary Circulation
Low oxygen blood leaves the heart through the Right Ventricle
Artery branches into capillaries and releases O2/CO2
Red blood comes back to the heart through Pulmonary veins
Enters Left Atrium
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Systemic Circulation
Red blood passes through the Left Atrium and Left Ventricle
Aorta carries blood and supplies the body
Branches into multitude of circulatory systems
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Pathway of the Heart
Right Atrim to Right Ventricle to Pulmonary Artery to Lung Capillary to Pulmonary Vein to Left Atrium to Left Ventricle to Aorta to Body Capillary to Vena Cava
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Plasma
55 percent of blood
-Dissolved with various ions
-Contains protien molecules that control BP and antibodies
-Contains fibrinogen that aids in clotting of blood
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Red Blood Cells
44 percent of blood
-Biconcave
-known as erythracyctes
-Red colour is hemoglobin, which is a protien contained iron and its job is to Transport nutriets mainly o2
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Hemoglobin function
Carries and transports O2/CO2
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White blood Cells
1 percent of blood
-Known as leucocytes
-produced in red bone marrow
-helps defend body against disease
-destroy bad cells with phagocytosis
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Platelets
Less than 1 percent of blood
-Shaped irregularly
-Purpose is to form blood clots
-have thromboplastin
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Blood Clotting Response
1. Platelets scrape the edges of broken tissue and release thromboplastin into the bloods plasma
2.Calcium ions become present and initiate clotting. Fibrinogen -> Fibrin
3.Frbrin forms threads and ropes to form a clot trapping red blood cells
4.The clot slowly contracts and pulls the wound together, seals the bloodflow
25
Universal Blood Acceptor
AB +
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Universal Blood Donor
O -
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Rh Factor
Positive or Negative aspect to blood, is a protien
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What happens if a clot forms inside a vessel
Severe brain/heart injury. Hemophilia is a common cause to this due to the disease causing improper blood clotting
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First Line of Defence
Skin, Hair, Eyelashes

-Physical barrier
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Second Line of Defence
Fevers and Sore Throats

-Body attacks the invader if it gets inside
-Macrophages attach and destroy the invader microbe
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Third Line of Defence
Antibiotics, Tcells, Bcells

-Antibody medicated immunity
1.Prevents pathogens
2.Attract macrophages to engulf and destroy
3.stimulate a reaction
32
Lymphocytes
T Cells
-Produces in bone marrow
-seek intruders
-identify antigens
-search for pathogens
B Cells
-Produce antibodies
-Memories are kept to retain info on the antigen
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