1What is the main function of the Respiratory System?
Supply the body with O2 and dispose of CO2
2Pulmonary Ventilation
mechanical process causing gas flow INTO and OUT of the lungs according to volume changes in thoracic cavity
3What is External Ventilation?
O2/CO2 exchange between air in lungs and blood (pulmonary arteries)
4What is Internal Ventilation?
O2 and CO2 exchange between blood (capillaries) and body tissues
5What is cellular respiration?
ATP production in the mitochondria
6Major Organs of Respiratory System?
nose, nasal cavity, paranasal sinuses, pharynx, larynx, trachea, bronchi and branches, lungs
7What is the Conducting Zone?
Respiratory passageways that convey air; filter, warm, and humidify incoming air
8What is the Respiratory Zone?
Respiratory bronchioles, alveolar ducts and alveoli; site of gas exchange
9What are the 2 types of mucous membrane that lines the Nasal Cavity?
Olfactory Mucosa (receptors for smell) and Respiratory Mucosa (pseudostratified ciliated columnar epithelium; cilia move mucus to throat)
10During Inhalation, nasal conchae & nasal mucosa ____, ______, and ____ air
filter, warm, and moisten
11Purpose of Paranasal sinuses
lighten the skull, secrete mucus, and help to warm and moisten air
12Inflammation of nasal mucosa
Rhinitis
13Rhinitis
Inflammation of nasal mucosa
14Infection of paranasal sinuses
Sinusitis
15Sinusitis
Infection of paranasal sinuses
16Describe structure of Pharynx
Muscular funnel-shaped tube that connects nasal cavity and mouth to larynx and esophagus
17What are the three regions of the Pharynx?
Nasopharynx, Oropharynx, and Laryngopharynx
18Nasopharynx
Superior to soft palate; air passageway only
19Oropharynx
from level of soft palate to epiglottis; air and food passageway
20Laryngopharynx
posterior to epiglottis; air and food passageway
21Functions of the Larynx
provides open airway, routes food and air into proper channels, produces sound (vocal cords)
22True vocal cords
vocal folds that vibrate to produce sound
23Glottis
vocal folds together with opening between them
24Vestibular folds
Superior folds (false vocal cords) that help to close glottis during swallowing
25Describe structure of Trachea
C-shaped cartilage rings;prevent collasping of trachea which allows esopahgus to expand during swallowing
26Carina
last cartilage ring before trachea splits into primary bronchi
27Trachealis Muscle
smooth muscle that connects posterior parts of cartilage
28What are the three layers of the Trachea?
Mucosa, Submucosa, Adventitia
29Trachea: Mucosa
ciliated pseudostratified epithelium with goblet cells
30Trachea: Submucosa
connective tissue with seromucous glands
31Trachea: Adventitia
outermost layer- connective tissue
32Trace an O2 molecule through lungs
Naris- Nasal Cavity- Nasopharynx- Oropharynx- Laryngopharynx- Larynx- Trachea- Primary Bronchus- Secondary Bronchus- Tertiary Bronchus- Multiple Bronchi- Bronchioles- Terminal Bronchiole- Respiratory Bronchiole- Alveolar Duct- (Alveolar Sac)- Alveolus- Respiratory Membrane- Pulmonary Capillary
33Alveoli
Main site of GAS exchange; 140 m2 surface area for gas exchange- approx. 400 million
34What are some structural changes of the Conducting Zone?
Cartilage rings become irregular playes; Epithelium changes from pseudostratified columnar to simple cuboidal; Cilia and goblet cells become sparse
35Smooth muscle in conducting zone…
forms helical bands around the smaller bronchi and bronchioles; airways widen with sympathetic stimulation and constrict under parasympathetic stimulation
36External Surface of alveoli is covered by….
web of pulmonary capllaries and network of elastic fibers
37What are the three types of cells in the ALEOLI
Type 1, Type 2, and aleolar macrophages
38Type 1 Alveolar Cell
most abundant cell; form simple squamous epithelium; for gas exchange
39Type 2 Alveolar Cell
scattered cuboidal cells that secrete surfactant and antomicrobial protiens
40Alveolar Macrophages
keep alveoli surfaces sterile; once dead use mucociliary escalator
41The layers of the Respiratory Membrane (0.5 micro m thick; gas exchanges occurs due to simple diffusion) consists of
Alveolar epithelium (type 1 cells), capillary endothelium, and fused basement membrane
42Apex
superior tip of lung
43Base
inferior broad surface of lung
44Hilum
Site for entery/exit of root (= blood vessels, bronchi, lymphatic vessels, & nerves)
45Right Lungs has _____ lobes seperated by the _____
3; oblique and horizontal fissure
46Left Lung has _____ lobes seperated by the ____
2; oblique fissure and has a medial cardiac notch due to heart
47Parietal Pleura
lines thoracic wall, diaphragm, around heart, and between lungs
48Visceral Pleura
covers external surface of lungs, following its contour and fissures
49Pleural Fluid
fills slitlike pleural cavity that reduces friction and causes the pleurae cling together during breathing
50Segements seperated by septa (10 on R and 8-10 on L)
Bronchopulmonary segments
51Pleurisy
inflammation of pleura; causes friction- results often from pneumonia
52Pleural Effusion
fluid accumulation in pleural cavity (ex. blood, blood filtrate)
53collapsed lung because of air in pleural cavity
Pneumothorax
54Pulmonary Arteries and Veins
carry blood to and from lungs for oxygenation
55Bronchial Arteries
provide lung tissue itself with oxygenated blood
56Inspiration
Inhalation- gases flow into lungs
57Expiration
Exhalation- gases flow out of lungs
58Quiet Inspiration
Active; main muscles- diaphragm and external intercostals
59Quiet Expiration
Passive; driven by elastic recoil force of lungs (elasticity)
60Forced Inspiration
Active; acessory muscles- pectoralis and sternocleidomastoid
61Forced Expiration
Active; accessory muscles- abdominals, latissimus dorsi, and internal intercostals
62Neural Control of Ventilation
Respiratory Centers (in medulla and pons generate baseline respiration rate and control depth and rateof breathing) and Chemoreceptors (central in medulla and peripheral in carotid and aortic bodies- are sensitive to Pco2, Po2, and ph levels and control rate and depth of breathing via Resp Center)
63Name 3 diseases that are considered COPD’s (which are causesd due to smoking)
Chronic Bronchitis (smoke), Emphysema (smoke), and Asthma (reversable COPD)
64COPD
Chronic Obstructive Pulmonary Disease