Micro CH 2

Study of disease

Study of the cause of a disease

development of disease

colonization of the body by pathogens

an abnormal state in which the body is not functionally normal

permantly colonize the host

may be present for days, weeks, or months

microbiota imbalance associated with disease

competition between microbes

microbes that cause harm-inducing infections (ecto vs. endo)

infectious organisms or agents that cause disease

the ability of an organism or agent to overcome host defenses (depends on host genetics/physiology and pathogen virulence factors

describes the level of harm caused by a pathogen following infection

Promote attachment and colonization of host tissues (invasion), facilitate pathogen spread from the initial site of infection (invasiveness), and have a toxic effect on cells/tissues/host physiology (toxins)

likely to cause disease after infection in a healthy host. They rapidly reproduce increase in number and have moderate to high virulence.

less likely to cause disease in a healthy host, have low virulence- not sufficient to cause disease by itself

A change in body function that is felt by a patient (YOU) as a result of disease

A change in a body that can be measureed or observed (BY DOC) as a result of disease

a specific group of signs and symptoms that accompany a disease (COMBO)

Incubation period (no s/s), prodromal period (mild s/s), period of illness (most severe s/s), period of decline (s/s), period of convalescence

Disease can spread during ALL five periods

between period of illness and disease- when most microbes/illness in body

illness is short term because the pathogen is eliminated by the host defenses- person is usually immune to reinfection

Illness persists over a long time period

Illness may recur if immunity weakens-ex is HIV